| Yamamoto T, Horii I, Yoshida T | |||
|---|---|---|---|
| Integrated NMR-based metabonomic investigation of early metabolic effects
of ethylene glycol monomethyl ether (egme) on male reproductive organs in rats |
|||
| J Toxicol Sci | 2007 | Dec;32(5):515-28 | PubMed |
| Tsujikawa K, Kuwayama K, Miyaguchi H, Kanamori T, Iwata Y, Inoue H, Yoshida T, Kishi T | |||
|---|---|---|---|
| Determination of muscimol and ibotenic acid in Amanita mushrooms by high-performance liquid chromatography and liquid chromatography-tandem mass spectrometry |
|||
| J Chromatogr B Analyt Technol Biomed Life Sci | 2007 | Jun 1;852(1-2):430-5 | PubMed |
| Naito S, Furuta S, Yoshida T, Kitada M, Fueki O, Unno T, Ohno Y, Onodera H, Kawamura N, Kurokawa M, Sagami F, Shinoda K, Nakazawa T, Yamazaki T |
|||
|---|---|---|---|
| Current opinion: safety evaluation of drug metabolites in development of
pharmaceuticals |
|||
| J Toxicol Sci | 2007 | Oct;32(4):329-41 | PubMed |
| Kim BC, Jeon WK, Hong HY, Jeon KB, Hahn JH, Kim YM, Numazawa S, Yosida
T, Park EH, Lim CJ |
|||
|---|---|---|---|
| The anti-inflammatory activity of Phellinus linteus (Berk. & M.A. Curt.)
is mediated through the PKCdelta/Nrf2/ARE signaling to up-regulation of heme oxygenase-1 |
|||
| J Ethnopharmacol | 2007 | Sep 5;113(2):240-7 | PubMed |
| Koyama K, Suzuki R, Yoshida T, Kikuno T | |||
|---|---|---|---|
| Usefulness of serum concentration measurement for acute pentobarbital
intoxication in patients |
|||
| Chudoku Kenkyu | 2007 | Jan;20(1):45-53 | PubMed |
| Ashino T, Arima Y, Shioda S, Iwakura Y, Numazawa S, Yoshida T | |||
|---|---|---|---|
| Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2
expressions in arthritic mouse liver |
|||
| Eur J Pharmacol | 2007 | Mar 8;558(1-3):199-207 | PubMed |
| Shindo S, Numazawa S, Yoshida T | |||
|---|---|---|---|
| A physiological role of AMP-activated protein kinase in phenobarbital-mediated constitutive androstane receptor activation and CYP2B induction |
|||
| Biochem J | 2007 | Feb 1;401(3):735-41 | PubMed |
2007
| Tsujikawa K, Kuwayama K, Miyaguchi H, Kanamori T, Iwata YT, Yoshida T, Inoue H | |||
|---|---|---|---|
|
Development of an on-site screening system for amphetamine-type stimulant
tablets with a portable attenuated total reflection Fourier transform infrared
spectrometer |
|||
| Anal Chim Acta | 2008 | Feb 4;608(1):95-103 | PubMed |
| Yoshida T | |||
|---|---|---|---|
|
Preparedness response to hazard and toxic incidents and food terrorism |
|||
| Yakugaku Zasshi | 2008 | Jun;128(6):851-7 | PubMed |
| Ashino T, Yamanaka R, Yamamoto M, Shimokawa H, Sekikawa K, Iwakura Y, Shioda
S, Numazawa S, Yoshida T. |
|||
|---|---|---|---|
|
Negative feedback regulation of lipopolysaccharide-induced inducible nitric
oxide synthase
gene expression by heme oxygenase-1 induction in macrophages. |
|||
| Mol Immunol | 2008 | Apr;45(7):2106-15 | PubMed |
| Kageyama H, Takenoya F, Hori Y, Yoshida T, Shioda S | |||
|---|---|---|---|
| Morphological interaction between galanin-like peptide- and dopamine-containing
neurons in the rat arcuate nucleus |
|||
| Regul Pept | 2008 | Jan 10;145(1-3):165-8 | PubMed |
| Hori Y, Kageyama H, Guan JL, Kohno D, Yada T, Takenoya F, Nonaka N, Kangawa
K, Shioda S, Yoshida T |
|||
|---|---|---|---|
| Synaptic interaction between ghrelin- and ghrelin-containing neurons in the rat
hypothalamus |
|||
| Regul Pept | 2008 | Jan 10;145(1-3):122-7 | PubMed |
| Numazawa S, Sakaguchi H, Aoki R, Taira T, Yoshida T | |||
|---|---|---|---|
|
Regulation of the
susceptibility to oxidative stress by cysteine availability in pancreatic
beta-cells. |
|||
| Am J Physiol Cell Physiol | 2008 | Aug;295(2):C468-74 | PubMed |
2008
| Tsujikawa K, Kuwayama K, Miyaguchi H, Kanamori T, Iwata YT, Yoshida T, Inoue H | |||
|---|---|---|---|
|
Determination of
salvinorin A and salvinorin B in Salvia divinorum-related products circulated in
Japan. |
|||
| Forensic Sci Int | 2008 | Sep 18;180(2-3):105-9 | PubMed |
| Tanaka S, Yamagishi R, Tsutsui M, Kishida T, Murakami M, Kuroda J, Yoshida T | |||
|---|---|---|---|
| Tissue- and dose-dependent alteration of stress-inducible proteins by beta2-adrenoceptor agonist, salbutamol, in rats. |
|||
| J Toxicol Sci | 2005 | Dec;30(4):305-14 | PubMed |
2005
| Numazawa S, Shindo S, Maruyama K, Chibana F, Kawahara Y, Ashino T, Tanaka S, Yoshida T | |||
|---|---|---|---|
| Impaired nuclear translocation of CAR in hepatic preneoplastic lesions:
Association with an attenuated CYP2B induction by phenobarbital |
|||
| FEBS Lett | 2005 | Jul 4;579(17):3560-4 | PubMed |
| Ishikawa M, Numazawa S, Yoshida T | |||
|---|---|---|---|
| Redox regulation of the transcriptional repressor Bach1 | |||
| Free Radic Biol Med | 2005 | May 15;38(10):1344-1352 | PubMed |
| Oguro T, Yoshida T | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Induction of stress responsive protein, heme oxygenase-1 and metallothionein-I
and -II by oxidative stress |
|||||||||
| Curr Top Pharmacol | 2004 | 8:265-275 | |||||||
| Kaneko S, Manabe A, Numazawa S, Itoh K, Inoue M, Yoshida T, Hisamitsu H, Sasa R | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Bisphenol-A contents in materials used in pediatric dentistry | |||||||||
| Pediat Dent J | 2004 | Oct;14:17-21 | |||||||
| Tanaka S, Momose Y, Tsutsui M, Kishida T, Kuroda J, Shibata N, Yoshida T, Yamagishi R | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Quantitative estimation of myocardial fibrosis based on receptor occupancy for beta2-adrenergic receptor agonists in rats |
|||||||||
| J Toxicol Sci | 2004 | Aug;29(3):179-86 | PubMed | ||||||
2004
| Numazawa S, Yoshida T | |||
|---|---|---|---|
| Nrf2-dependent gene expressions: a molecular toxicological aspect | |||
| J Toxicol Sci | 2004 | May;29(2):81-89 | PubMed |
| Ashino T, Oguro T, Shioda S, Horai R, Asano M, Sekikawa K, Iwakura Y, Numazawa S, Yoshida T |
|||
|---|---|---|---|
| Involvement of interleukin-6 and tumor necrosis factor alpha in CYP3A11
and 2C29 down-regulation by Bacillus Calmette-Guerin and lipopolysaccharide in mouse liver |
|||
| Drug Metab Dispos | 2004 | Jul;32(7):707-714 | PubMed |
2003
| Tanaka S, Tsuchida A, Kiuchi Y, Oguchi K, Numazawa S, Yoshida T | |||
|---|---|---|---|
| GABAergic modulation of hippocampal glutamatergic neurons: an in vivo microdialysis study | |||
| Eur J Pharmacol | 2003 | Mar 28;465(1-2):61-7 | PubMed |
| Numazawa S, Ishikawa M, Yoshida A, Tanaka S, Yoshida T | |||
|---|---|---|---|
| Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress | |||
| Am J Physiol Cell Physiol | 2003 | Aug;285(2):C334-342 | PubMed |
| Numazawa S, Watabe M, Nishimura S, Kurosawa M, Izuno M, Yoshida T | |||
|---|---|---|---|
| Regulation of ERK-mediated signal transduction by p38 MAP kinase in human monocytic THP-1 cells | |||
| J Biochem (Tokyo) | 2003 | May;133(5):599-605 | PubMed |
| Ashino T, Ozawa S, Numazawa S, Yoshida T | |||
|---|---|---|---|
| Tissue-dependent induction of heme oxygenase-1 and metallothionein-1/2 by methyl methanesulfonate | |||
| J Toxicol Sci | 2003 | Aug;28(3):181-189 | PubMed |
| Watabe M, Isogai Y, Numazawa S, Yoshida T | |||
|---|---|---|---|
| Role of c-Myc in nitric oxide-mediated suppression of cytochrome P450 3A4 | |||
| Life Sci | 2003 | Nov 21;74(1):99-108 | PubMed |
2002
| Asano T, Ishihara K, Wakui Y, Yanagisawa T, Kimura M, Kamei H, Yoshida T, Kuroiwa Y, Fujii Y, Yamashita M, Kuramochi T, Tomisawa H, Tateishi M |
|||
|---|---|---|---|
| Absorption, distribution and excretion of 3H-labeled cephaeline- and emetine-spiked ipecac syrup in rats | |||
| Eur J Drug Metab Pharmacokinet | 2002 | Jan-Mar;27(1):17-27 | PubMed |
| Asano T, Watanabe J, Sadakane C, Ishihara K, Hirakura K, Wakui Y, Yanagisawa T, Kimura M, Kamei H, Yoshida T, Fujii Y, Yamashita M |
|||
|---|---|---|---|
| Biotransformation of the ipecac alkaloids cephaeline and emetine from ipecac syrup in rats | |||
| Eur J Drug Metab Pharmacokinet | 2002 | Jan-Mar;27(1):29-35 | PubMed |
| Kobayashi Y, Suzuki M, Ohshiro N, Sunagawa T, Sasaki T, Oguro T, Tokuyama S, Yamamoto T, Yoshida T |
|||
|---|---|---|---|
| Induction and inhibition of cytochrome P450 and drug-metabolizing enzymes by climbazole | |||
| Biol Pharm Bull | 2002 | Jan;25(1):53-57 | PubMed |
| Oguro T, Takahashi Y, Ashino T, Takaki A, Shioda S, Horai R, Asano M, Sekikawa K, Iwakura Y, Yoshida T |
|||
|---|---|---|---|
| Involvement of tumor necrosis factor alpha, rather than interleukin-1alpha/beta
or nitric oxides in the heme oxygenase-1 gene expression by lipopolysaccharide in the mouse liver |
|||
| FEBS Lett | 2002 | Apr 10;516(1-3):63-66 | PubMed |
2001
| Sasaki M, Nakayama M, Numazawa S, Oguro T, Honma S, Iwamura S, Tsukamoto K, Yoshida T | |||
|---|---|---|---|
| Cytochrome P450 enzymes involved in the metabolic pathway of the histamine 2 (H2)-receptor antagonist roxatidine acetate by human liver microsomes |
|||
| Arzneimittelforschung | 2001 | 51(8):651-658 | PubMed |
| Asano T, Kushida H, Sadakane C, Ishihara K, Wakui Y, Yanagisawa T, Kimura
M, Kamei H, Yoshida T |
|||
|---|---|---|---|
| Metabolism of ipecac alkaloids cephaeline and emetine by human hepatic microsomal cytochrome P450s, and their inhibitory effects on P450 enzyme activities |
|||
| Biol Pharm Bull | 2001 | Jun;24(6):678-682 | PubMed |
| Kobayashi K, Kogo M, Tani M, Shimada N, Ishizaki T, Numazawa S, Yoshida
T, Yamamoto T, Kuroiwa Y, Chiba K |
|||
|---|---|---|---|
| Role of CYP2C19 in stereoselective hydroxylation of mephobarbital by human liver microsomes | |||
| Drug Metab Dispos | 2001 | Jan;29(1):36-40 | PubMed |
| Kurosawa M, Tani Y, Nishimura S, Numazawa S, Yoshida T | |||
|---|---|---|---|
| Distinct PKC isozymes regulate bufalin-induced differentiation and apoptosis in human monocytic cells | |||
| Am J Physiol Cell Physiol | 2001 | Mar;280(3):C459-464 | PubMed |
| Oda M, Kurosawa M, Numazawa S, Tanaka S, Akizawa T, Ito K, Maeda M, Yoshida T | |||
|---|---|---|---|
| Determination of bufalin-like immunoreactivity in serum of humans and rats by time-resolved fluoroimmunoassay for using a monoclonal antibody |
|||
| Life Sci | 2001 | Jan 26;68(10):1107-1117 | PubMed |
| Oguro T, Yoshida T | |||
|---|---|---|---|
| Effect of ultraviolet A on ornithine decarboxylase and metallothionein gene expression in mouse skin | |||
| Photodermatol Photoimmunol Photomed | 2001 | Apr;17(2):71-78 | PubMed |
| Kobayashi Y, Ohshiro N, Sasaki T, Tokuyama S, Tobe T, Yoshida T, Yamamoto T | |||
|---|---|---|---|
| Effect of 4-(4-chlorobenzyl)pyridine on rat hepatic microsomal cytochrome P450 and drug-metabolizing enzymes in vivo and in vitro |
|||
| Biol Pharm Bull | 2001 | May;24(5):505-509 | PubMed |
| Tanaka S, Okuno Y, Numazawa S, Yamamoto T, Shioda S, Yoshida T | |||
|---|---|---|---|
| Brain responses to acute withdrawal in phenobarbital-dependent rats | |||
| Eur J Pharmacol | 2001 | Jun 8;421(2):101-108 | PubMed |
| Kobayashi Y, Suzuki M, Ohshiro N, Sunagawa T, Sasaki T, Tokuyama S, Yamamoto
T, Yoshida T |
|||
|---|---|---|---|
| Climbazole is a new potent inducer of rat hepatic cytochrome P450 | |||
| J Toxicol Sci | 2001 | Aug;26(3):141-150 | PubMed |

(2001~ の研究業績を記してあります。)
2011
|
Ashino T, Sudhahar V, Urao N, Oshikawa J, Chen GF, Wang H, Huo Y, Finney L, Vogt S, McKinney RD, Maryon EB, Kaplan JH, Ushio-Fukai M, Fukai T |
|||
|---|---|---|---|
|
Unexpected role of the copper transporter ATP7A in PDGF-induced vascular
smooth muscle cell migration |
|||
| Circ Res | 2010 | Sep 17;107(6):787-99 | PubMed |
|
Watanabe H, Tohyama M, Kamijima M, Nakajima T, Yoshida T, Hashimoto K, Iijima M |
|||
|---|---|---|---|
|
Occupational trichloroethylene hypersensitivity syndrome with human herpesvirus-6
and cytomegalovirus reactivation |
|||
| Dermatology | 2010 | Aug;221(1):17-22 | PubMed |
2010
|
Tanaka S, Tsutsui M, Kishida T, Souma S, Kuroda J, Yoshida T |
|||
|---|---|---|---|
|
Salbutamol
inhibits lipopolysaccharide-induced inflammatory responses in rat peritoneal
macrophages |
|||
| J Toxicol Sci | 2010 | 35(3):327-34 | PubMed |
|
Kaizaki A, Tanaka S, Tsujikawa K, Numazawa S, Yoshida T |
|||
|---|---|---|---|
|
Recreational drugs, 3,4-Methylenedioxymethamphetamine(MDMA), 3,4-methylenedioxyamphetamine
(MDA) and diphenylprolinol, inhibit neurite outgrowth in PC12 cells |
|||
| J Toxicol Sci | 2010 | 35(3):375-81 | PubMed |
|
Tanaka S, Kondo H, Kanda K, Ashino T, Nakamachi T, Sekikawa K, Iwakura Y, Shioda S, Numazawa S, Yoshida T |
|||
|---|---|---|---|
|
Involvement of interleukin-1 in lipopolysaccaride-induced microglial activation
and learning and memory deficits |
|||
| J Neurosci Res | 2011 | Apr;89(4):506-14 | PubMed |
|
Numazawa S, Sugihara K, Miyake S, Tomiyama H, Hida A, Hatsuno M, Yamamoto M, Yoshida T |
|||
|---|---|---|---|
|
Possible involvement of oxidative stress in 5-fluorouracil-mediated myelosuppression
in mice |
|||
| Basic Clin Pharmacol Toxicol | 2011 | Jan;108(1):40-5 | PubMed |
| Takahashi M, Nagashima M, Suzuki J, Seto T, Yasuda I, Yoshida T | |||
|---|---|---|---|
|
Creation and application of psychoactive designer drugs data library using
liquid chromatography with photodiode array spectrophotometry detector
and gas chromatography-mass spectrometry |
|||
| Talanta | 2009 | Feb 15;77(4):1245-72 | PubMed |
2009
| Kojima M, Ashino T, Yoshida T, Iwakura Y, Sekimoto M, Degawa M | |||
|---|---|---|---|
|
IL-1 regulates
the Cyp7a1 gene and serum total cholesterol level at steady state in
mice. |
|||
| Biochem Biophys Res Commun | 2009 | Feb 6;379(2):239-42 | PubMed |
| Fukano Y, Yoshimura H, Yoshida T | |||
|---|---|---|---|
| Heme oxygenase-1 gene expression in human alveolar epithelial cells (A549)
following exposure to whole cigarette smoke on a direct in vitro exposure system |
|||
| Exp Toxicol Pathol | 2006 | Jul;57(5-6):411-8 | PubMed |
| Kaizaki A, Tanaka S, Ishige K, Numazawa S, Yoshida T | |||
|---|---|---|---|
| The neuroprotective effect of heme oxygenase (HO) on oxidative stress in HO-1 siRNA-transfected HT22 cells |
|||
| Brain Res | 2006 | Sep 7;1108(1):39-44 | PubMed |
| Fukano Y, Oishi M, Chibana F, Numazawa S, Yoshida T | |||
|---|---|---|---|
| Analysis of the expression of heme oxygenase-1 gene in human alveolar epithelial cells exposed to cigarette smoke condensate |
|||
| J Toxicol Sci | 2006 | May;31(2):99-109 | PubMed |
| Tanaka S, Ide M, Shibutani T, Ohtaki H, Numazawa S, Shioda S, Yoshida T | |||
|---|---|---|---|
| Lipopolysaccharide-induced microglial activation induces learning and memory deficits without neuronal cell death in rats |
|||
| J Neurosci Res | 2006 | Mar;83(4):557-66 | PubMed |
| Nishimaki-Mogami T, Kawahara Y, Tamehiro N, Yoshida T, Inoue K, Ohno Y, Nagao T, Une M | |||
|---|---|---|---|
| 5Alpha-bile alcohols function as farnesoid X receptor antagonists |
|||
| Biochem Biophys Res Commun | 2006 | Jan 6;339(1):386-91 | PubMed |
2006