Sasama Y, Yoshimura K, Hoshino M, Sasa K, Akaike T, Morita M, Baba K, Shirota T, Miyamoto Y:
Supersulfides support bone growth by promoting chondrocyte proliferation in the growth plates. J Oral Biosci, 66(1), 76-81, 2024
2023
原著
Minami E, Sasa K,Yamada A, Kawai R, Yoshida H, Nakano H, Maki K, Kamijo R:
Lactate-induced histone lactylation by p300 promotes osteoblast differentiation. PLoS One,18(12), e0293676, 2023
Ono S, Yamada A, Tanaka J, Yukimori A, Sasa K, Mishima K, Funatsu T, Kamijo R:
BMP-2-mediated signaling suppresses salivary gland development. Biochem Biophys Res Commun, 681, 1-6, 2023
Uto S, Hikita A, Mori D, Sakamoto T, Yano F, Ohba S, Saito T, Takato T, Hoshi K.
Subcutaneously Transplanted Fresh Cartilage in Allogeneic and Xenogeneic Immunocompetent Mouse. Tissue Eng Part A. 2023 Oct;29 (19-20):541-556.
Kawai R, Sugisaki R, Miyamoto Y, Yano F, Sasa K, Minami E, Maki K, Kamijo R:
Cathepsin K degrades osteoprotegerin to promote osteoclastogenesis in vitro. In Vitro Cell Dev Biol Anim, 59(1), 10-18, 2023
Nishida R, Suzuki D, Akimoto Y, Matsubara S, Hayakawa J, Ushiyama A, Sasa K, Miyamoto Y, Iijima T, Kamijo R:
Exploring the pathophysiological mechanism of interstitial edema focusing on the role of macrophages and their interaction with the glycocalyx. J Oral Biosci, 65(1), 111-118, 2023
Nagasaki K, Yamada A, Sasa K, Kamijo R:
Kielin/chordin-like protein enhances induction of osteoblast differentiation by Bone Morphogenetic Protein-2. FEBS Open Bio., 13(7), 1357-1364, 2023
2022
原著
Nagata K, Hojo H, Chang SH, Okada H, Yano F, Chijimatsu R, Omata Y, Mori D, Makii Y, Kawata M, Kaneko T, Iwanaga Y, Nakamoto H, Maenohara Y, Tachibana N, Ishikura H, Higuchi J, Taniguchi Y, Ohba S, Chung UI, Tanaka S, Saito T.
Runx2 and Runx3 differentially regulate articular chondrocytes during surgically induced osteoarthritis development. Nat Commun. 2022 Oct 19;13(1):6187. doi: 10.1038/s41467-022-33744-5.
Itose M, Suzawa T, Shibata Y, Ohba S, Ishikawa K, Inagaki K, Shirota T, Kamijo R:
Knee meniscus regeneration using autogenous injection of uncultured adipose tissue-derived regenerative cells. Regen Ther, 21:398-405, 2022.
Tachibana N, Chijimatsu R, Okada H, Oichi T, Taniguchi Y, Maenohara Y, Miyahara J, Ishikura H, Iwanaga Y, Arino Y, Nagata K, Nakamoto H, Kato S, Doi T, Matsubayashi Y, Oshima Y, Terashima A, Omata Y, Yano F, Maeda S, Ikegawa S, Seki M, Suzuki Y, Tanaka S and Saito T.
RSPO2 defines a distinct undifferentiated progenitor in the tendon/ligament and 5 suppresses ectopic ossification. Sci Adv. 2022 Aug 19;8(33):eabn2138. doi: 10.1126/sciadv.abn2138. Epub 2022 Aug 19.
Yano F, Takeda T, Kurokawa T, Tsubaki T, Chijimatsu R, Inoue K, Tsuji S, Tanaka S, Saito T.
Effects of conditioned medium obtained from human adipose-derived stem cells on skin inflammation. Regen Ther. 2022 Apr 16;20:72-77. doi: 10.1016/j.reth.2022.03.009.
Kaneko K, Miyamoto Y, Ida T, Morita M, Yoshimura K, Nagasaki K, Toba K, Sugisaki R, Motohashi H, Akaike T, Chikazu D, Kamijo R:
8-Nitro-cGMP suppresses mineralization by mouse osteoblasts. J Clin Biochem Nutr, 71: 191-197, 2022
Tanaka M, Miyamoto Y, Sasa K, Yoshimura K, Yamada A, Shirota T, Kamijo R:
Low oxygen tension suppresses the death of chondrocyte-like ATDC5 cells induced by interleukin-1β. In Vitro Cellular & Developmental Biology - Animal, 58(7), 521-528, 2022
Ikezaki-Amada K, Miyamoto Y, Sasa K, Yamada A, Kinoshita M, Yoshimura K, Kawai R, Yano F, Shirota T, Kamijo R.
Extracellular acidification augments sclerostin and osteoprotegerin production by Ocy454 mouse osteocytes. Biochem. Biophys. Res. Commun., 597, 44-51, 2022
Takizawa H, Karakawa A, Suzawa T, Chatani M, Ikeda M, Sakai N, Azetsu Y, Takahashi M, Urano E, Kamijo R, Maki K, Takami M:
Neural crest-derived cells possesses differentiateon potentiall to keratinocytes in the processs of wound healing. Biomedicine & Pharmacotherapy, 146, 112593, 2022
Asakawa T, Yamada A, Kugino M, Hasegawa T, Yoshimura K, Sasa K, Kinoshita M, Nitta M, Nagata K, Sugiyama T, Kamijo R, Funatsu T:
Establishment of Down’s syndrome periodontal ligament cells by transfection with SV40T-Ag and hTERT. Human Cell, 35(1), 379-383, 2022
Kaneko T, Horiuchi K, Chijimatsu R, Mori D, Nagata K, Omata Y, Yano F, Inui H, Moro T, Tanaka S, Saito T.
Regulation of osteoarthritis development by ADAM17/Tace in articular cartilage. Journal of Bone and Mineral Metabolism. 2022 Mar; 40(2):196-207.
Yamaguchi T, Hosomichi K, Shirota T, Miyamoto Y, Ono W, Ono N.
Primary failure of tooth eruption: Etiology and management. Japanese Dental Science Review, 58, 258-267, 2022
Kinoshita M, Yamada A, Sasa K, Ikezaki K, Shirota T, Kamijo R.
Phorbol-12-myristate 13-acetate inhibits Nephronectin gene expression via Protein kinase C alpha and c-Jun/c-Fos transcription factors. Scientific Reports, 11(1), 20360, 2021
Nakamoto H, Katanosaka Y, Chijimatsu R, Mori D, Xuan F, Yano F, Omata Y, Maenohara Y, Murahashi Y, Kawaguchi K, Yamagami R, Inui H, Taketomi S, Taniguchi Y, Kanagawa M, Naruse K, Tanaka S, Saito T.
Involvement of Transient Receptor Potential Vanilloid Channel 2 in the Induction of Lubricin and Suppression of Ectopic Endochondral Ossification in Mouse Articular Cartilage. Arthritis Rheumatol. 2021 Aug;73(8):1441-1450. doi: 10.1002/art.41684. Epub 2021 Jul 5.
Maenohara Y, Chijimatsu R, Tachibana N, Uehara K, Xuan F, Mori D, Murahashi Y, Nakamoto H, Oichi T, Chang SH, Matsumoto T, Omata Y, Yano F, Tanaka S, Saito T:
Lubricin Contributes to Homeostasis of Articular Cartilage by Modulating Differentiation of Superficial Zone Cells. J Bone Miner Res., 36, 792-802, 2021
Yoshida Y, Yamada A, Akimoto Y, Abe K, Matsubara S, Hayakawa J, Tanaka J, Kinoshita M, Kato T, Ogata H, Sakashita A, Mishima K, Kubota Y, Kawakami H, Kamijo R, Iijima T:
Cdc42 has important roles in postnatal angiogenesis and vasculature formation. Dev. Biol., 477, 64-69, 2021
Yoshida H, Suzawa T, Shibata Y, Takahashi M, Kawai R, Takami M, Maki K, Kamijo R,
Neural crest-derived cells in nasal conchae of adult mice contribute to bone regeneration, Biochem. Biophys. Res. Commun. , 554, 173-178, 2021
Takimoto R, Suzawa T, Yamada A, Sasa K, Miyamoto Y, Yoshimura K, Sasama Y. Tanaka M, Kinoshita M, Ikezaki K, Ichikawa M, Yamamoto M, Shirota T, Kamijo R,
Zoledronate promotes inflammatory cytokine expression in human CD14-positive monocytes among peripheral mononuclear cells in presence of γδ T cells. Immunology 162 (3): 306-313, 2021
Sato Y, Koyama S, Ohkubo C, Ogura S, Kamijo R, Sato S, Aida J, Izumi Y, Atsumi M, Isobe A, Baba S, Ikumi N, Watanabe F. Dental implant care and trouble among dependent patients based on the questionnaire survey among Japanese dental practitioners. BMC Oral Health, 20:335, 341, 2020.
Kato T, Mizobuchi M, Sasa K, Yamada A, Ogata H, Honda H, Sakashita A, Kamijo R.
Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells in Uremic Rats. Biochemical and Biophysical Research Communications. 532(1) 11-18, 2020.
Shibuya I, Takami M, Kawamoto M, Karakawa A, Nakamura S, Kamijo R.
Immunohistochemical analysis of the distribution of RANKL-expressing cells and the expression of Osteoclast-related markers in gigant cell tumor of bone. J. Hard Tissue Biol. 29(3), 1-10, 2020
Kurotaki, Y., Sakai, N., Miyazaki, T., Hosonuma, M., Sato, Y., Karakawa, A., Chatani, M., Myers, M., Suzawa, T., Negishi-Koga, T., Kamijo, R., Miyazaki, A., Maruoka, Y., Takami, M.
Effects of lipid metabolism on mouse incisor dentinogenesis. Sci Rep, 10(1), 5102, 2020
Matsumoto A, Takami M, Urano E, Nakamachi T, Yoshimura K, YamadaA, Suzawa T, Miyamoto Y, Baba K, Kamijo R
Lipopolysaccharide (LPS) Inhibits Ectopic Bone Formation Induced by Bone Morphogenetic Protein-2 and TGF-β1 through IL-1β Production. J. Oral Biosci. 62, 44-51, 2020
Sugisaki R, Miyamoto Y, Yoshimura K, Sasa K, Kaneko K, Tanaka M, Itose M, Inoue S, Baba K, Shirota T, Chikazu D, Kamijo R
Possible involvement of elastase in enhanced osteoclast differentiation by neutrophils through degradation of osteoprotegerin. Bone 132:115216, 2020
Izumida E, Suzawa T, Miyamoto Y, Yamada A, Otsu M, Saito T, Yamaguchi T, Nishimura K, Ohtaka M, Nakanishi M, Yoshimura K, Sasa K, Takimoto R, Uyama R, Shirota T, Maki K, Kamijo R.
Functional analysis of PTH1R variants found in primary failure of eruption. J. Dent. Res. 99(4), 429-436, 2020.
Suzawa, T., Yoshida, H., Takahashi, M., Itose, M., Takimoto, R., Sasama, Y., Tanaka, M., Ikezaki, K., Shirota, T., Maki, K., Kamijo, R.
Prospects of neural crest-derived cells from oral and dentofacial tissues for application in regenerative medicine. Oral Science International, 17(3):115-125, 2020.
須澤徹夫、笹清人、吉村健太郎、山田篤、宇山理紗、宮本洋一、上條竜太郎．
「神経堤由来細胞：再生医療の自家細胞ソースとしての可能性（The potential of neural crest-derived cells as autologous cell source for regenerative medicine）」 月刊「細胞」52(4): 39-43, 2020
その他
上條竜太郎 「新しい生活様式における私のステイホーム」 昭和大学新聞 9月号
上條竜太郎 「今号の見どころ」日本口腔インプラント学会誌 32 (4)
2019
原著
Imai H, Yoshimura K, Miyamoto Y, Sasa K, Sugano M, Chatani M, Takami M, Yamamoto M, Kamijo R.
Roles of monocarboxylate transporter subtypes in promotion and suppression of osteoclast differentiation and survival on bone. Sci. Rep. 9(1): 15608, 2019
Shibuya I, Takami M, Miyamoto A, Karakawa A, Dezawa A, Nakamura S, Kamijo R. In vitro study of the effects of Denosumab on giant cell tumor of bone: Comparison with Zoledronic acid Pathol Oncol Res. 25(1):409-419, 2019
Kato M, Tanaka J, Aizawa R, Yajima-Himuro S, Seki T, Tanaka K, Yamada A, Ogawa M, Kamijo R, Tsuji T, Mishima K, Yamamoto M.
Visualization of junctional epithelial cell replacement by oral gingival epithelial cells over a life time and after gingivectomy. Sci. Rep. 9(1): 7640, 2019
Aizawa R, Yamada A, Seki T, Tanaka J, Nagahama R, Ikehata M, Kato T, Sakashita A, Ogata H, Chikazu D, Maki K, Mishima K, Yamamoto M, Kamijo R.
Cdc42 regulates cranial suture morphogenesis and ossification. Biochem Biophys Res Commun.512(2) 145–149, 2019
Kato T, Yamada A, Sasa K, Yoshimura K, Morimura N, Ogata H, Sakashita A, Kamijo R.
Nephronectin expression is inhibited by inorganic phosphate in osteoblasts. Calcif Tissue Int.104(2) 201–206, 2019.
Nagayama K, Miyamoto Y, Kaneko K, Yoshimura K, Sasa K, Akaike T, Fujii S, Izumida E, Uyama R, Chikazu D, Maki K, Kamijo R.
Production of 8-nitro-cGMP in osteocytic cells and its upregulation by parathyroid hormone and prostaglandin E2. In Vitro Cellular & Developmental Biology - Animal. 55(1):45-51,2019.
Manome Y, Suzuki D, Nishida R, Yamada A, Miyamoto Y, Funatsu T, Kamijo R.
Immunotherapy for malignant tumors with focus on toll-like receptors. Oral Science International, 16(1): 3-7, 2019.
Mochizuki A, Nakayama K, Nakamura S, Dantsuji M, Kamijo R, Shioda S,Sakurai T, Ozeki M, Inoue T Involvement of orexin in lipid accumulation in the liver J Oral Biosci. 60(3):76-82,2018
Sasa K, Yoshimura K, Yamada A, Suzuki D, Miyamoto Y, Imai H, Nagayama K, Maki K, Yamamoto M, Kamijo R.
Monocarboxylate transporter-1 promotes osteoblast differentiation via suppression of p53, a negative regulator of osteoblast differentiation Sci. Rep. 8,10579,2018
Manome Y, Suzuki D, Mochizuki A, Saito E, Sasa K, Yoshimura K, Inoue T, Takami M, Inagaki K, Funatsu T, Kamijo R.
The inhibition of malignant melanoma cell invasion of bone by the TLR7 agonist R848 is dependent upon pro-inflammatory cytokines produced by bone marrow macrophages Oncotarget, 9(52):29934-29943,2018
Ikehata M, Yamada A, Fujita K, Yoshida Y, Kato T, Sakashita A, Ogata H, Iijima T, Kuroda M, Chikazu D, Kamijo R. Cooperation of Rho family proteins Rac1 and Cdc42 in cartilage development and calcified tissue formation Biochem Biophys Res Commun, 500,525-529,2018
Kato T, Yamada A, Ikehata M, Yoshida Y, Sasa K, Morimura N, Sakashita A, Iijima T, Chikazu D, Ogata H, Kamijo R.
FGF-2 suppresses expression of nephronectin via JNK and PI3K pathways. FEBS Open Bio, 8(5),836-84,2018
Kaneko K, Miyamoto Y, Tsukuura R, Sasa K, Akaike T, Fujii S, Yoshimura K, Nagayama K, Hoshino M, Inoue K, Maki K, Baba K, Chikazu D, Kamijo R.
8-Nitro-cGMP is a promoter of osteoclast differentiation induced by RANKL. Nitric Oxide, 72(1),46-51,2018
Watanabe E, Yamagata Y, Fujitani J, Fujishima I, Takahashi K, Uyama R, Ogoshi H, Kojo A, Maeda H, Ueda K, Kayashita J.
The Criteria of Thickened Liquid for Dysphagia Management in Japan. Dysphagia, 33(1),26-32,2018
A preliminary report on dental implant condition among dependent elderly based on the survey amomng Japanese dental practioners.
Sato Y, Koyama S, Ohkubo C, Ogura S, Kamijo R, Sato S, Aida J, Izumi Y, Atsumi M, Isobe A, Baba S, Ikumi N, Watanabe F. Int J Implant Dent. 8;4(1):14, 2018
Iezumi Y, Yamada A, Minami E, Ikehata M, Yoshida Y, Kato T, Morimura N, Ogata H, Sakashita A, Iijima T, Chikazu D, Kamijo R.
IL-1b suppresses nephronectin expression in osteoblasts nia ERK1/2 and JNK. Biochem Biophys Res Commun, 493(1),773-775,2017
Rodriguez R, Yoshimura K, Shibata Y, Miyamoto Y, Tanaka R, Uyama R, Sasa K, Suzuki D, Miyazaki T, Kamijo R.
Nanoindentation time-dependent deformation/recovery suggestive of methylglyoxal induced glycation in calcified nodules. Nanomedicine. 2017 Nov;13(8):2545-2553.
Suzuki D, Bush J, Bryce DM , Kamijo R, Beier F
Rac1 dosage is crucial for normal endochondral bone growth. Endocrinology, 158(10): 3386-3398, 2017
Hoshino M, Kaneko K, Miyamoto Y, Yoshimura K, Suzuki D, Akaike T, Sawa T, Ida T, Fujii S, Ihara H, Tanaka J, Tsukuura R, Chikazu D, Mishima K, Baba K, Kamijo R
8-Nitro-cGMP promotes bone growth through expansion of growth plate cartilage. Free Rad Biol Med 110: 63-71, 2017
Enomoto, T., Takami, M., Yamamoto, M., Kamijo, R.
LPS administration increases CD11b+ c-Fms+ CD14+ cell population that possesses osteoclast differentiation potential in mice. Cytotechnology, 69(3): 529-537, 2017
Urano-Morisawa E, Takami M, Suzawa T, Matsumoto A, Osumi N, Baba K, Kamijo R.
Induction of osteoblastic differentiation of neural crest-derived stem cells from hair follicles. PLoS ONE, 12(4):e0174940, 2017
Ikehata M, Yamada A, Morimura N, Itose M, Suzawa T, Shirota T, Chikazu D, Kamijo R.
Wnt/ß-catenin signaling activates nephronectin expression in osteoblasts. Biochem Biophys Res Commun, 484: 231-234, 2017
Yamaguchi T, Hosomichi K, Yano K, Kim YI, Nakaoka H, Kimura R, Otsuka H, Nonaka N, Haga S, Takahashi M, Shirota T, Kikkawa Y, Yamada A, Kamijo R, Park SB, Nakamura M, Maki K, Inoue I
Comprehensive genetic exploration of selective tooth agenesis of mandibular incisors by exome sequencing. Human Genome Variation, 4: 17005, 2017
Funato S, Yasuhara R, Yoshimura K, Miyamoto Y, Kaneko K, Suzawa T, Chikazu D, Mishima K, Baba K, Kamijo R. Extracellular matrix loss in chondrocytes after exposure to interleukin-1β in NADPH oxidase-dependent manner. Cell Tissue Res, 368: 135-144, 2017
Saito E, Suzuki D, Kurotaki D, Mochizuki A, Manome Y, Suzawa T, Toyoshima Y,Ichikawa T, Funatsu T, Inoue T, Takami M, Tamura T, Inagaki K, Kamijo R.
Down-regulation of Irf8 by Lyz2-cre/loxP accelerates osteoclast differentiation in vitro. Cytotechnology, 69(3): 443-450, 2017
Miyamoto Y, Akaike T, Kawabata S, Akuta T, Taruki C, Yoshitake J, Hamada S, Ota F, Igarashi H, Yoshimura K, Kamijo R, Maeda H
Degradation of bradykinin by a metalloendopeptidase from Streptococcus pyogenes J Oral Biosci 58(4): 167-172, 2016
Hiranuma K, Yamada A, Kurosawa T, Aizawa R, Suzuki D, Saito Y, Nagahama R, Ikehata M, Tsukasaki M, Morimura N, Chikazu D, Maki K, Shirota T, Takami M, Yamamoto M, Iijima T, Kamijo R.
Expression of nephronectin is enhanced by α,25-dihydroxyvitamin D3. FEBS Open Bio., 6: 914-918, 2016
Konno A, Nishimura A, Nakayama S, Mochizuki A, Yamada A, Kamijo R, Inoue T, Iijima T.
Continuous monitoring of caspase-3 activation induced by propofol in developing mouse brain. Int. J. Dev. Neurosci., 51: 42-49, 2016
Kurosawa T, Yamada A, Suzuki D, Morimura N, Sasagane Y, Itabe H, Kamijo R.
Nephronectin expression is up-regulated by BMP-2. Biol. Pharm. Bull., 39: 1211-1215, 2016
Saito A, Yoshimura K, Miyamoto Y, Kaneko K, Chikazu D, Yamamoto M, Kamijo R.
Enhanced and suppressed mineralization by acetoacetate and β-hydroxybutyrate in osteoblast cultures. Biochem Biophys Res Commun. 473 (2016) 537-544
Oshima-Nakayama M, Yamada A, Kurosawa T, Aizawa R, Suzuki D, Saito Y, Kassai H, Sato Y, Yamamoto M, Shirota T, Aiba A , Maki K, Kamijo R.
Cdc42 is crucial for facial and palatal formation during craniofacial development. Bone Reports, 5:1-6, 2016
Nagahama R, Yamada A, Tanaka J, Aizawa R, Suzuki D, Kassai H, Yamamoto M, Mishima K, Aiba A , Maki K, Kamijo R.
Rho GTPase protein Cdc42 is criticak for postnatal cartilage development. Biochem Biophys Res Commun, 470: 813-817, 2016
総説
Suzawa T, Yoshida H, Itose M, Takimoto R, Saito E, Suzuki D, Inagaki K, Shirota T, Maki K, Kamijo R.
Neural crest-derived cells in the oral and maxillofacial regions of adult mice: isolation and application for regenerative medicine. Showa Univ J Med Sci, 28(3):209-217, 2016
Yamada A, Kamijo R.
Nephronectin: an extracellular matrix protein with diverse in vivo functions. J.Dent & Oral Disord., 2(1), 2016
鈴木 大、馬目瑤子、斎藤愛美、上條竜太郎.
口腔におけるカルシウム制御とアンチエイジング（Importance of Calcium Metabolism for Oral Health and Anti-Aging Strategies） 日本抗加齢医学会雑誌（Antiaging Medicine）Vol.12(2),41-46, 2016
上條竜太郎
国際歯科研究学会（International Association for Dental Research）ソウル大会 日本歯科医師会雑誌 vol 69, No. 6, 54-56 (638-640) 2016
2015
原著
Wang X, Suzawa T, Miyauchi T, Zhao B, Yasuhara R, Anada T, Nakamura M, Suzuki O, Kamijo R.
Synthetic Octacalcium Phosphate Enhanced Reparative Dentin Formation via Induction of Odontoblast Differentiation. J Tissue Eng Regen Med, 9: 1310-1320, 2015
Yu, J., Murakami, M., Aoki, T., Jiang, B., Jin Z, Koizumi, T., Kusano, M., Kamijo, R., Miyamoto, Y., Enami, Y., Watanabe, M., Otsuka, K.
Oxygenated Static Preservation of Donation after Cardiac Death Liver Grafts Improves Hepatocyte Viability and Function. Eur. Surg. Res., 56:1-18, 2015
Suzuki H, Mochizuki A, Yoshimura K, Miyamoto Y, Kaneko K, Inoue T, Chikazu D, Takami M, Kamijo R
Bropirimine inhibits osteoclast differentiation through production of interferon-β. Biochem Biophys Res Commun, 467:146-151, 2015
Ono M, Suzawa T, Takami M, Yamamoto G, Hosono T, Yamada A, Suzuki D, Yoshimura K, Watahiki J, Hayashi R, Arata S, Mishima K, Nishida K, Osumi N, Maki K. Kamijo R.
Localization and osteoblastic differentiation potential of neural crest-derived cells in oral tissues of adult mice. Biochem Biophys Res Commun, 464: 1209-1214, 2015
Saito Y, Yamada A, Suzuki D, Tanaka J, Nagahama R, Kurosawa T, Maki K, Mishima K, Shirota T, Kamijo R.
Association of aging with gene expression profiling in mouse submandibular glands. Genomics Data, 5: 115-119, 2015
Wurihan, Yamada A, Suzuki D, Shibata Y, Kamijo R, Miyazaki T.
Enhanced in vitro biological activity generated by surface characteristics of anodically oxidized titanium ― the contribution of the oxidation effect. European Cells & Materials, 29: 290-302, 2015
Kurosawa T, Yamada A, Takami M, Suzuki D, Saito Y, Hiranuma K, Enomoto T, Morimura N, Yamamoto M, Iijima T, Shirota T, Itabe H, Kamijo R
Expression of Nephronectin is inhibited by Oncostatin M via both JAK/STAT and MAPK pathways. FEBS Open Bio, 5: 303-307, 2015
Matsunaga A, Takami M, Irie T, Mishima K, Inagaki K, Kamijo R
Microscopic study on resorption of beta-tricalcium phosphate materials by osteoclasts. Cytotechnology, 67: 727-732, 2015
Maruyama, N., Shibata, Y., Mochizuki, A., Yamada, A., Maki, K., Inoue, T., Kamijo, R., Miyazaki, T.
Bone micro-fragility caused by the mimetic aging processes in a-Klothodeficient mice: in situ nanoindentation assessment of dilatational bands. Biomaterials, 47:62-71, 2015
Suzuki W, Yamada A, Aizawa R, Suzuki D, Kassai H, Harada T, Nakayama M, Nagahama R, Maki K, Takeda S, Yamamoto M, Aiba A, Baba K, Kamijo R
Cdc42 is critical for cartilage development during endochondral ossification. Endocrinol. 156 : 314-322, 2015
Miyamoto S, Miyamoto Y, Shibata Y, Yoshimura K, Izumida E, Suzuki H, Miyazaki T, Maki K, Kamijo R
In-situ quasi-static and dynamic nanoindentation assessment of calcified nodules: Implication of glucocorticoids responsible for osteoblast calcification. Acta Biomater 12:216-226, 2015
Ikumi N, Suzawa T, Yoshimura K, Kamijo R
Bone Response to Static Compressive Stress at Bone-Implant Interface: The Pilot Study of Critical Static Compressive stress. Int J Oral Maxillofac Implants, 30: 827-833, 2015
Maruyama N, Shibata Y, Wurihan, Swain MV, Kataoka Y, Takiguchi Y, Yamada A, Maki K, Miyazaki T
Strain-rate stiffening of cortical bone: observations and implications from nanoindentation experiments. Nanoscale, 6: 14863-14871, 2014
Funato S, Matsunaga A, Oh K, Miyamoto Y, Yoshimura K, Tanaka J, Suzuki D, Uyama R, Suzuki H, Mishima K, Nakamura M, Namiki O, Baba K, Inagaki K, Kamijo R
Effects of antibody to receptor activator of nuclear factor κ-B ligand on inflammation and cartilage degradation in collagen antibody-induced arthritis in mice. J Neg Results BioMed 13:18, 2014
Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, Hoshino M, Imamura T, Akiyama C, Yasuhara R, Mishima K, Maruyama T, Kohda C, Tanaka K, Potempa J, Yasuda H, Baba K, Kamijo R.
Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-α and interleukin-1β but suppresses that by interleukin-17A. Importance of proteolytic degradation of osteoprotegerin by lysine gingipain. J Biol Chem 289:15621-15630, 2014
Takahashi M, Suzawa T, Yamada A, Yamaguchi T, Mishima K, Osumi N, Maki K, Kamijo R
Identification of gene expression profile of neural crest-derived cells isolated from submandibular glands of adult mice. Biochem Biophys Res Commun, 446:481-486, 2014
Jang IK, Tanaka R, Wurihan, Suzuki D, Shibata Y, Fujisawa N, Tanimoto Y, Ogura K, Kamijo R, Miyazaki T
Nanomechanical properties and molecular structures of in vitro mineralized tissues on anodically-oxidized titanium surfaces. Nanomedicine 10(3):629-637, 2014
総説
Miyamoto Y
Molecular mechanisms for bone resorption by gingipains: Degradation of osteoprotegerin by lysine-specific gingipain is a key factor for enhanced osteoclastogenesis. J Oral Biosci 56: 120-124, 2014
Yamada A, Aiba A, Kamijo R
Rho family small G proteins: lessons from tissue-specific gene knockout studies. J Oral Biosci 56(1):23-29, 2014
Aizawa R, Yamada A, Suzuki D, Tsukasaki M, Yamamoto M, Aiba A, Kamijo R
Cdc42 plays important roles in bone formation during limb development. Jpn. J. Tissue Cult. Dent. Res., 22(2), 35-41, 2013
Matsumoto T, Yamada A, Aizawa R, Suzuki D, Tsukasaki M, Suzuki W, Nakayama M, Maki K, Yamamoto M, Baba K, Kamijo R.
BMP-2 induced expression of Alx3 that is a positive regulator of osteoblast differentiation. PLoS ONE 5(6):e68774, 2013
Shibata Y, Suzuki D, Wurihan, Yamada A, Maruyama N, Fujisawa N, Kamijo R, Miyazaki T.
Lysyl oxidase like-2 reinforces unsatisfactory ossification induced by bone morphogenetic protein-2. Nanomedicine, 1036-1047, 2013
Shibuya I, Yoshimura K, Miyamoto Y, Yamada A, Takami M, Suzawa T, Suzuki D, Ikumi N, Hiura F, Anada T, Suzuki O, Kamijo R.
Octacalcium phosphate suppresses chondrogenic differentiation of ATDC5 cells. Cell Tissue Res 352:401-412, 2013
Maruyama T, Miyamoto Y, Yamamoto G, Yamada A, Yoshimura K, Suzawa T, Takami M, Akiyama T, Hoshino M, Iwasa F, Ikumi N, Tachikawa T, Mishima K, Baba K, Ryutaro Kamijo R.
Downregulation of carbonic anhydrase IX promotes Col10a1 expression in chondrocytes. PLoS ONE 8(2):e56984, 2013
総説
高見正道、松永朗裕、稲垣克記、上條竜太郎
抗 RANKL 抗体の開発と臨床応用. THE BONE 27(4):71-79, 2013
Suzuki D, Yamada A, Kamijo R
The Essential Roles of Small GTPase Rac1 in Limb Development. J Oral Biosci, 55, 116-121, 2013
Miyamoto Y.
A search for backseat players in regulation of differentiation and function of cells constituting hard tissues – Phagocyte-type NADPH oxidase, monocarboxylate transporter-1, and lysine gingipain. Dent Med Res 33 (1): 51-55, 2013
Takami M, Miyamoto A, Matsumoto A, Mochizuki A, Tachi K, Baba K, Inoue T, Mijung Y, Shibuya I, Zhao B, Kamijo K.
Functions of Toll-like receptors in osteoclast differentiation induced by receptor activator of NF-kB ligand. The New Frontiers in Research for Oral Cancer, Tokyo, MARUZEN PLANET. CO. LTD. 35-49, 2013
Yamada A, Matsumoto T, Suzuki D, Funato S, Takami M, Aizawa R, Suzawa T, Miyamoto Y, Suzuki W, Yoshimura K, Nakayama M, Tsukasaki M, Maki K, Yamamoto M, Baba K, Kamijo R,
Screening for regulators of osteoblast differentiation induced by BMP-2. The New Frontiers in Research for Oral Cancer, Tokyo, MARUZEN. CO. LTD. 81-89, 2013
その他
上條竜太郎
国際歯科研究学会（International Association for Dental Research）シアトル大会 日本歯科医師会雑誌 vol 66, No. 3, 299-300 (95-96) 2013
宮本洋一
昭和大学歯科病院で私立大学戦略的研究基盤形成支援事業 平成24年度合同シンポジウム開催. the Quintessence, 32 (5): 150, 2013
Mochizuki A, Takami M, Miyamoto Y, Nakamaki T, Tomoyasu S, Kadono Y, Tanaka S, Inoue T, Kamijo R.
Cell adhesion signal regulates RANK expression in osteoclast precursors. PLoS ONE 7(11):e48795, 2012
Yu J, Choi S, Park ES, Shin B, Yu J, Lee SH, Takami M, Kang JS, Meong H, Rho J.
D-chiro-inositol Negatively Regulates the Formation of Multinucleated Osteoclasts by Down-Regulating NFATc1. J Clin Immunol. 32(6):1360-1371, 2012
Iwai-Yoshida M, Shibata Y, Wurihan, Suzuki D, Fujisawa N, Tanimoto Y, Kamijo R, Maki K, Miyazaki T.
Antioxidant and osteogenic properties of anodically oxidized titanium. Journal of the Mechanical Behavior of Biological Materials, 13:230-236, 2012
Miyamoto A, Takami M, Matsumoto A, Mochizuki A, Yamada T, Tachi K, Shibuya I, Nakamichi T, Shioda S, Baba K, Inoue T, Miyamoto Y, Yim M, Kamijo R.
R848, a Toll-like receptor 7 agonist, inhibits osteoclast differentiation but not survival or bone-resorbing function of mature osteoclasts. Cytotechnology, 64:331-339, 2012
Pal SK, Noguchi S, Yamamoto G, Yamada A, Isobe T, Hayashi S, Tanaka J, Tanaka Y, Kamijo R, Yamane G, Tachikawa T.
Expression of MAL (myelin and lymphocyte protein) in oral carcinogenesis. Medical Molecular Morphology, 45:222-228, 2012
Tsukasaki M, Yamada A, Yoshimura K, Miyazono A, Yamamoto M, Takami M, Miyamoto Y, Kamijo R.
Nephronectin expression is regulated by SMAD signaling in osteoblast-like MC3T3-E1 cells. Biochem Biophys Res Commun, 425:390-392, 2012
Koyama T, Nakajima C, Nishimoto S, Takami M, Woo JT, Yazawa K.
Suppressive Effects of the Leaf of Terminalia catappa L. on Osteoclast Differentiation In Vitro and Bone Weight Loss In Vivo. J Nutr Sci Vitaminol. 58(2):129-35, 2012
Suzuki D, Yamada A, Aizawa R, Funato S, Matsumoto T, Suzuki W, Takami M, Miyamoto Y, Suzawa T, Yamamoto M, Baba K, Kamijo R.
BMP2 differentially regulates expression of Gremlin1 and Gremlin2, negative regulators of BMP function, during osteoblast differentiation. Calcif. Tissue Int., 91 (1), 88-96, 2012
Aizawa R, Yamada A, Suzuki D, Iimura T, Kassai H, Harada T, Tsukasaki M, Yamamoto G, Tachikawa T, Nakao K, Yamamoto M, Yamaguchi A, Aiba A, Kamijo R.
Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech. Dev., 129 (1-4), 38-50, 2012
Murakami A, Arimoto T, Suzuki D, Iwai-Yoshida M, Otsuka F, Shibata Y, Igarashi T, Kamijo R, and Miyazaki T
Antimicrobial and osteogenic properties of a hydrophilic-modified nanoscale hydroxyapatite coating on titanium. Nanomedicine, 8(3) 374-382, 2012
Yamamoto M, Kato T, Hotta C, Nishiyama A, Kurotaki D, Yoshinari M, Takami M, Ichino M, Nakazawa M, Matsuyama T, Kamijo R, Kitagawa S, Ozato K and Tamura T
Shared and Distinct Functions of the Transcription Factors IRF4 and IRF8 in Myeloid Cell Development PLoS One, 2011, 6(10); e25812
Ono M, Suzawa T, Takami M, Miyauchi T, Ogasawara A, Yamada A, Hosono T, Arata S, Miyamoto Y, Baba K, Nakamura M, Osumi N, Maki K, Kamijo R
Identification and isolation of neural crest derived cells in nasal concha. Jpn. J. Tissue Cult. Dent. Res., 20(2), 29-35, 2011
Tsukasaki M, Yamada A, Suzuki D, Aizawa R, Miyazono A, Miyamoto Y, Suzawa T, Takami M, Yoshimura K, Morimura N, Yamamoto M, Kamijo R
Expression of POEM, a positive regulator of osteoblast differentiation, is suppressed by TNF-α. Biochem Biophys Res Commun, 410: 766-770, 2011
Dranovsky A, Picchini AM, Moadel T, Yamada A, Kimura S, Leonardo ED, Hen R
Experience dictates stem cell fate in the adult hippocampus. Neuron, 70(5): 908-923, 2011
Yoshimura K, Miyamoto Y, Yasuhara R, Maruyama T, Akiyama T, Yamada A, Takami M, Suzawa T, Tsunawaki S, Tachikawa T, Baba K, Kamijo R
Monocarboxylate transporter-1 is required for cell death in mouse chondrocytic ATDC5 cells exposed to interleukin-1β via late phase activation of nuclear factor κB and expression of phagocyte-type NADPH oxidase. J Biol Chem, 286 (17): 14744-14752, 2011
Tachi K, Takami M, Sato H, Mochizuki A, Zhao B, Miyamoto Y, Tsukasaki H, Inoue T, Shintani S, Koike T, Honda Y, Suzuki O, Baba K, Kamijo R
Enhancement of bone morphogenetic protein-2-induced ectopic bone formation by transforming growth factor β1. Tissue Eng Part A, 17:597-606, 2011
総説
Yasuhara R, Miyamoto Y
Roles of gingipains in periodontal bone loss. J Oral Biosci, 53 (3):197-205, 2011
Hasegawa S, Yonezawa T, Ahn JY, Cha BY, Teruya T, Takami M, Yagasaki K, Nagai K, Woo JT.
Honokiol inhibits osteoclast differentiation and function in vitro. Biol Pharm Bull, 33(3):487-92, 2010
Yamada M, Miyauchi T, Yamamoto A, Iwasa F, Takeuchi M, Anpo M, Sakurai K, Baba K, Ogawa T.
Enhancement of adhesion strength and cellular stiffness of osteoblasts on mirror-polished titanium surface by UV-photofunctionalization. Acta Biomater, 6(12): 4578-88, 2010
Tachi K, Takami M, Zhao B, Mochizuki A, Yamada A, Miyamoto Y, Inoue T, Baba K, Kamijo R
Bone morphogenetic protein 2 enhances mouse osteoclast differentiation via increased levels of receptor activator of NF-κB ligand expression in osteoblasts. Cell Tissue Res 342:213-220, 2010
Shibata Y, Suzuki D, Omori S, Tanaka R, Murakami A, Kataoka Y, Baba K, Kamijo R, Miyazaki T
The characteristics of in vitro biological activity of titanium surfaces anodically oxidized in chloride solutions. Biomaterials 31:8546-8555, 2010
Wang X, Suzawa T, Ohtsuka H, Zhao B, Miyamoto Y, Miyauchi T, Nishimura R, Inoue T, Nakamura M, Baba K, Kamijo R
Carbonic anhydrase II regulates differentiation of ameloblasts via intracellular pH-dependent JNK signaling pathway. J Cell Physiol 225:709-719, 2010
Nojima J, Kanomata K, Takada Y, Fukuda T, Kokabu S, Ohte S, Takada T, Yamamoto TS, Sasanuma H, Yoneyama K, Ueno N, Okazaki Y, Kamijo R, Yoda T, Katagiri T
Dual roles of SMAD proteins in the conversion from myoblasts to osteoblastic cells by bone morphogenetic proteins. J Biol Chem, 285:15577-15586, 2010
Miyauchi T, Yamada M, Yamamoto A, Iwasa F, Suzawa T, Kamijo R, Baba K, Ogawa T
The enhanced characteristics of osteoblast adhesion to photofunctionalized nanoscale TiO2 layers on biomaterials surfaces. Biomaterials, 31:3827-3839, 2010
総説
Miyamoto Y, Kamijo R
Overview: Molecular regulation of mineralization and its failure - from disclosure of mechanisms to clinical implications - J Oral Biosci, 52:1-5, 2010
著書
Kamijo R, Zhao B, Mochizuki A, Inoue T, Takami M
Involvement of transcription factor IRF-8 in bone metastasis of cancer. The Waksman Foundation of Japan Inc. Report of Researches in 2009, 43-47, 2010
その他
宮本洋一
昭和大学歯学部でハイテク・リサーチセンタープロジェクト研究成果発表会と口腔癌包括的研究センター公開シンポジウムが開催される． the Quintessence, 98 (5):82-183, 2010
Takami M, Mochizuki A, Yamada A, Tachi K, Zhao B, Miyamoto Y, Anada T, Honda Y, Inoue T, Nakamura M, Suzuki O, Kamijo R
Osteoclast differentiation induced by synthetic octacalcium phosphate through receptor activator of NF-kB ligand expression in osteoblasts. Tissue Eng Part A, 15:3991-4000, 2009
Okano A, Miyamoto Y, Asari J, Kamijo R, Inoue M
Change in salivary levels of chromogranin A in children by hearing dental air turbine noise. Pediatr Dent J, 19:220-227, 2009
Suzuki D, Yamada A, Amano T, Yasuhara R, Kimura A, Sakahara M, Tsumaki N, Takeda S, Tamura M, Nakamura M, Wada N, Nohno T, Shiroishi T, Aida A, Kamijo R
Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development. Dev Biol, 335:396-406, 2009
Zhao B, Takami M, Yamada A, Wang X, Koga T, Hu X, Tamura T, Ozato K, Choi Y, Ivashkiv B. L, Takayanagi H, Kamijo R
Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis. Nat Med, 15:1066-1071, 2009
Yasuhara R, Miyamoto Y, Takami M, Imamura T, Potempa J, Yoshimura K, Kamijo R
Lysine-specific gingipain promotes lipopolysaccharide- and active-vitamin D3-induced osteoclast differentiation by degrading osteoprotegerin. Biochem J, 419:159-166, 2009
Odaira M, Aoki T, Miyamoto Y, Yasuhara R, Jin Z, Yu J, Nishino N, Yamada K, Kusano T, Hayashi K, Yasuda D, Koizumi T, Mitamura K, Enami Y, Niiya T, Murai N, Kato H, Shimizu Y, Kamijo R, Kusano M
Cold preservation of the liver with oxygenation by a two-layer method. J Surg Res, 152:209-217, 2009
Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, Takami M, Donnelly RP, Itabe H, Yamamoto M, Kimura S, Kamijo R
IFN-γ down-regulates Secretoglobin 3A1 gene expression. Biochem Biophys Res Commun 379:964-968, 2009
Tomita T, Yamada A, Miyakoshi M, Kido T, Sheikh F, Srisodsai A, Miyajima A, Donnelly RP, Kimura S
Oncostatin M regulates Secretoglobin 3A1 and 3A2 expression in a bidirectional manner. Am J Respir Cell Mol Biol, 40:620-630, 2009
総説
Jimi E, Takami M, Hiraga T, Nakamura I, Urade M, Miyamoto Y
The light and dark side of bisphosphonates. J Oral Biosci, 51: 177-187, 2009
Suzuki D, Yamada A, Amano T, Kimura A, Yasuhara R, Sakahara M, Tamura M, Tsumaki N, Takeda S, Nakamura M, Shiroishi T, Aiba A, Kamijo R（分担執筆）
Generation of Rac1 conditional mutant mice by Cre/loxP system. Shioda S, Homma I, Kato N (Eds.) Transmitters and Modulators in Health and Disease. New Frontiers in Neuroscience. Tokyo, 2009, Springer, pp175-178
その他
宮本洋一
昭和大学が２つのイベントを開催．昭和大学大学院歯学研究科ハイテク・リサーチ・センタープロジェクト平成20年度研究成果発表会および昭和大学歯学部口腔癌包括的研究センター平成20年度公開シンポジウム． the Quintessence, 28 (5): 178, 2009
2008
原著
Anada T, Kumagai T, Honda Y, Masuda T, Kamijo R, Kamakura S, Yoshihara N, Kuriyagawa T, Shimauchi H, Suzuki O
Dose-dependent osteogenic effect of octacalcium phosphate on mouse bone marrow stromal cells. Tissue Eng Part A, 14:965-978, 2008
Kawatani M, Okumura H, Honda K, Kanoh N, Muroi M, Dohmae N, Takami M, Kitagawa M, Futamura Y, Imoto M, Osada H
The identification of an osteoclastogenesis inhibitor through the inhibition of glyoxalase I. Proc Natl Acad Sci USA, 105:11691-11696, 2008
Zhao B, Takami M, Miyamoto Y, Suzawa T, Yamada A, Mochizuki A, Yasuhara R, Wang X, Namiki M, Sakamoto K, Kamijo R
Characterization of synovial cell clones isolated from rheumatoid arthritis patients: possible involvement of TNF-a in reduction of osteoprotegerin in synovium. Cytokine, 41:61-70, 2008
Takahashi N, Udagawa N, Kobayashi Y, Takami M, Martin TJ, Suda T（分担執筆）
Osteoclast Generation. Bilezikian JP, Raisz LG, Rodan GA (Eds.) Principles of Bone Biology (Third edition) San Diego, 2008, Academic Press, pp173-190
2007
原著
Yamada A, Takami M, Kawawa T, Yasuhara R, Zhao B, Mochizuki A, Miyamoto Y, Eto T, Yasuda H, Nakamichi Y, Kim N, Katagiri T, Suda T, Kamijo R
Interleukin-4 inhibition of osteoclast differentiation is stronger than that of Interleukin-13 and they are equivalent for induction of osteoprotegerin production from osteoblasts. Immunology, 120:573-579, 2007
Irie A, Takami M, Kubo H, Sekino-Suzuki N, Kasahara K, Sanai Y
Heparin enhances osteoclastic bone resorption by inhibiting osteoprotegerin activity. Bone, 41:165-174, 2007
Miyazono A, Yamada A, Morimura N, Takami M, Suzuki D, Kobayashi M, Tezuka K, Yamamoto M, Kamijo R
TGF-β suppresses POEM expression through ERK1/2 and JNK in osteoblasts. FEBS Lett, 581:5321-5326, 2007
Nakagawa H, Hasumi K, Takami M, Aida-Hyugaji S, Woo J-T, Nagai K, Ishikawa T, Wachi M
Identification of two biologically-crucial hydroxygroups of (-)-epigallocatechin gallate in osteoclast culture. Biochem Pharmacol,73:34-43, 2007
Yasuhara R, Suzawa T, Miyamoto Y, Wang X, Takami M, Yamada A, Kamijo R
Nitric Oxide in Pulp Cell Growth, Differentiation and Mineralization. J Dent Res, 86:163-168, 2007
Ishima Y, Sawa T, Kragh-Hansen U, Miyamoto Y, Matsushita S, Akaike T, Otagiri M
S-Nitrosylation of human variant albumin Liprizzi (R410C) confers potent antibacterial and cytoprotective properties. J Pharmacol Exp Ther, 320:969-977, 2007
Fukuda T, Kanomata K, Nojima J, Urakawa I, Suzawa T, Imada M, Kukita A, Kamijo R, Yamashita T, Kakagiri T
FGF23 induces expression of two isoforms of NAB2, which are corepressors of Egr-1. Biochem Biophys Res Commun, 353:147-151, 2007
Oikawa A, Kobayashi M, Okamatsu Y, Shinki T, Kamijo R, Yamamoto M, Hasegawa K
Mitogen-activated protein kinases mediate interleukin-1 beta-induced receptor activator of nuclear factor-kappaB ligand expression in human periodontal ligament cells. J Periodontal Res, 42:367-376, 2007
Masuda T, Takahashi I, Arai F, Anada T, Miyamoto Y, Fukuda T, Suzuki O
A new configuration device for mechanical stress culture. Proceedings of International Symposium on Micro-Nano Mechatronics and Human Science, 418-423, 2007
著書
Zhao B, Katagiri T, Toyoda H, Takada T, Takaoka K, Kamijo R
Heparin enhances BMP activity by maintaining high levels of nuclear phosphorylated Smad1/5/8. Honma and Shioda (Eds.) In New Frontiers in Regenerative Medicine Tokyo, 2007, pp37-42
2006
原著
Zhao B, Katagiri T, Toyoda H, Takada T, Fukuda T, Chung UI, Koike T, Takaoka K, Kamijo R
Heparin potentiates the in vivo ectopic bone formation induced by bone morphogenetic protein-2. J Biol Chem, 281:23246-23253, 2006
Uchida T, Arai F, Suzuki O, Ichikawa A, Fukuda T, Katagiri T, Kamijo R, Nakamura M, Numata M, Watanabe N
Differentiation and monitoring of cells using a biochip for regenerative medicine : Differentiation of bone marrow stromal cells and myoblasts, JSME Int J Series C 49: 852-858, 2006
Suzuki O, Kamakura S, Katagiri T, Nakamura M, Zhao B, Honda Y, Kamijo R
Bone formation enhanced by implanted octacalcium phosphate involving conversion into Ca-deficient hydroxyapatite. Biomaterials, 27:2671-2681, 2006
Suzawa T, Itoh N, Takahashi N, Katagiri T, Morimura N, Kobayashi Y, Yamamoto T, Kamijo R.
Establishment of primary cultures for mouse ameloblasts as a model of their lifetime. Biochem Biophys Res Commun, 345:1247-1253, 2006
Mochizuki A, Takami M, Kawawa T, Suzumoto R, Sasaki T, Shiba A, Tsukasaki H, Zhao B, Yasuhara R, Suzawa T, Miyamoto Y, Choi Y, Kamijo R
Identification and Characterization of the Precursors Committed to Osteoclasts Induced by TRANCE/RANKL. J Immunol, 177:4360-4368, 2006
Yang Q, Kurotani R, Yamada A, Kimura S, Gonzalez FJ
PPARα activation during pregnancy severely impairs mammary lobuloalveolar development in mice. Endocrinology, 147:4772-4780, 2006
Kodaira K, Imada M, Goto M, Tomoyasu A, Fukuda T, Kamijo R, Suda T, Higashio K, Katagiri T
Purification and identification of a BMP-like factor from bovine serum. Biochem Biophys Res Commun, 345:1224-1231, 2006
Yang Q, Yamada A, Kimura S, Peters JM, Gonzalez FJ
Alterations in skin and stratified epithelia by constitutively activated PPARα. J Invest Dermatol, 126: 374-385, 2006
Woo J-T, Kawatani M, Kato M, Shinki T, Yonezawa T, Kanoh N, Nakagawa H, Takami M, Stern P, Nagai K, Osada H
Reveromycin A, a novel agent for osteoporosis inhibits bone resorption by inducing apoptosis in activated osteoclasts. Proc Natl Acad Sci USA, 103: 4729-4734, 2006
Shimazaki M, Miyamoto Y, Yamamoto K, Yamada S, Takami M, Shinki T, Udagawa N, Shimizu M
Analogs of 1a,25-dihydroxyvitamin D3 with high potency in induction of osteoclastogenesis and prevention of dendritic cell differentiation: Synthesis and biological eveluation of 2-substituted 19-norvitamin D analogs. Bioorg Med Chem, 14: 4645-4656, 2006
総説
Takami M, Mochizuki A, Suzumoto R, Sasaki T
Differentiation of osteoclats and dendritic cells from common precursors: relationships between bone metabolism and immune system. Biolog Mechanism Tooth Eruption, Resorption, and Movement, 143-149, 2006
Yamada A, Sheikh F, Niimi T, DeMayo FJ, Keegan AD, Donnelly RP, Kimura S
Induction of uteroglobin-related protein 2 (Ugrp2) gene expression by the Th2 cytokines IL-4 and IL-13. J Immunol, 175: 5708-5715, 2005
Yamada A, Kimura S
Induction of uteroglobin-related protein 2 (Ugrp2) expression by EGF and TGFα. FEBS Lett, 579: 2221-2225, 2005
Yasuhara R, Miyamoto Y, Akaike T, Akuta T, Nakamura M, Takami M, Morimura N, Yasu K, Kamijo R
Interleukin-1β induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxgen species-dependent manner. Biochem J, 389: 315-323, 2005
Takami M, Cho ES, Lee SY, Kamijo R, Yim M
Phosphodiesterase inhibitors stimulate osteoclast formation via TRANCE/RANKL expression in osteoblasts: possible involvement of ERK and p38 MAPK pathways. FEBS Lett, 579: 832-838, 2005
Kim N, Kadono Y, Takami M, Lee J, Lee SH, Okada F, Kim JH, Kobayashi T, Odgren PR, Nakano H, Yeh WC, Lee SK, Lorenzo JA, Choi Y
Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. J Exp Med, 202: 589-595, 2005
Suzumoto R, Takami M, Sasaki T
Differentiation and function of osteoclasts cultured on bone and cartilage. J Electlon Microscorpy, 54: 529-540, 2005
Takami M, Cho ES, Lee SY, Kamijo R, Yim M
Phosphodiesterase inhibitors stimulate osteoclast formation via TRANCE/RANKL expression in osteoblasts: possible involvement of ERK and p38 MAPK pathways. FEBS Lett, 579: 832-838, 2005
Arai F, Suzuki O, Uchida T, Ichikawa A, Fukuda T, Katagiri, T, Kamijo R, Nakamura M, Numata M, Watanabe N
Differentiation and monitoring of cells using a biochip for regenerative medicine. 2005, Transaction of the Japanese Society of Mechanical Engineers, 71C, pp3239-3245
Iwamoto K, Miyamoto T, Sawatani Y, Hosogane N, Hamaguchi I, Takami M, Nomiyama K, Takagi K, Suda T
Dimer formation of receptor activator of nuclear factor κB induces incomplete osteoclast formation. Biochem Biophys Res Commun. 325: 229-234, 2004
Suda K, Udagawa N, Sato N, Takami M, Itoh K, Woo JT, Takahashi N, Nagai K
Suppression of osteoprotegerin expression by prostaglandin E2 is crucially involved in lipopolysaccharide-induced osteoclast formation. J Immunol, 172: 2504-2510, 2004
Cheng X, Kinosaki M, Takami M, Choi Y, Zhang H, Murali R.
Disabling of receptor activator of nuclear factor-kappaB (RANK) receptor complex by novel osteoprotegerin-like peptidomimetics restores bone loss in vivo. J Biol Chem, 279: 8269-8677, 2004
Nukaga J, Kobayashi M, Shinki T, Song H, Takada T, Takiguchi T, Kamijo R, Hasegawa T
Regulatory effects of interleukin-1β and prostaglandin E2 on expression of receptor activator of nuclear factor-κB ligand in human periodontal ligament cells. J Periodontol, 75: 249-59, 2004
総説
Rho J, Takami M, Choi Y
Osteoimmunology: interactions of the immune and skeletal systems. Mol Cells, 29: 1-9, 2004
著書
Takada T, Katagiri T, Ifuku M, Morimura N, Kobayashi M, Hasegawa K, Ogamo A, Kamijo R
Enhancement of biological activity of BMP by heparin. In Davidovitch Z, Mah J (eds.) Biological Mechanisms of Tooth Movement and Craniofacial Adaptation. Boston, 2004, Harvard Society for the Advancement of Orthodontics, pp 197-203
2003
原著
Hosogane N, Shinki T, Kasuga H, Taketomi S, Toyama Y, Suda T
Mechanisms for the reduction of 24,25-dihydroxyvitamin D3 levels and bone mass in 24-hydroxylase transgenic rats. FASEB J, 17: 737-739, 2003
Takemoto F, Shinki T, Yokoyama K, Inokami T, Hara S, Yamada A, Kurokawa K, Uchida S
Gene expression of vitamin D hydroxylase and megalin in the remnant kidney of nephrectomized rats. Kidney Int, 64: 414-420, 2003
Ueno Y, Shinki T, Nagai Y, Murayama H, Fujii K, Suda T
In vivo administration of 1,25-dihydroxyvitamin D3 suppresses the expression of RANKL mRNA in bone of thyroparathyroidectomized rats constantly infused with PTH. J Cell Biochem, 90: 267-277, 2003
Watanabe N, Tezuka Y, Matsuno K, Miyatani S, Morimura N, Yasuda M, Fujimaki R, Kuroda K, Hiraki Y, Hozumi N, Tezuka K
Suppression of differentiation and proliferation of early chondrogenic cells by Notch. J Bone Mineral Res, 21: 344-352, 2003
Takada T, Katagiri T, Ifuku M, Morimura N, Kobayashi M, Hasegawa K, Ogamo A, and Kamijo R
Sulfated polysaccharides enhance the biological activities of bone morphogenetic proteins. J Biol Chem, 278: 43229-43235, 2003
Takami M, Suda K, Sahara T, Itoh K, Nagai K, Sasaki T, Udagawa N, Takahashi N
Involvement of vacuolar H+-ATPase in incorporation of risedronate into osteoclasts. Bone, 32: 341-349, 2003
Nakagawa H, Takami M, Udagawa N, Sawae Y, Suda K, Sasaki T, Takahashi N, Wachi M, Nagai K, Woo JT
Destruxins, cyclodepsipeptides, block the formation of actin rings and prominent clear zones and ruffled borders in osteoclasts. Bone, 33: 443-455, 2003
Li X, Udagawa N, Takami M, Sato N, Kobayashi Y, Takahashi N
p38 Mitogen-activated protein kinase is crucially involved in osteoclast differentiation but not in cytokine production, phagocytosis, or dendritic cell differentiation of bone marrow macrophages. Endocrinology, 144: 4999-5005, 2003
Itoh K, Udagawa N, Kobayashi K, Suda K, Li X, Takami M, Okahashi N, Nishihara T, Takahashi N
Lipopolysaccharide promotes the survival of osteoclasts via Toll-like receptor 4, but cytokine production of osteoclasts in response to lipopolysaccharide is different from that of macrophages. J Immunol, 170: 3688-95, 2003
Suda T, Ueno Y, Fujii K, Shinki T
Vitamin D and bone. J Cell Biochem, 88:259-266, 2003
Sahara T, Itoh K, Debari K, Sasaki T
Specific biological functions of vacuolar-H+-ATPase and lysosomal cysteine proteinase, cathepsin K, in osteoclasts. Anat Rec, 240A: 152-161, 2003
Tanaka S, Akaike T, Fang J, Beppu T, Ogawa M, Tamura F, Miyamoto Y, Maeda H
Antiapoptotic effect of haem oxygenase-1 induced by nitric oxide in experimental solid tumour. Br J Cancer, 88: 902-909, 2003
総説
Suda T, Ueno Y, Fujii K, Shinki T
Vitamin D and bone. J Cell Biochem, 88:259-266, 2003
Toyoshima T, Kamijio R, Takizawa K, Nakanishi Y, Nagumo M
Inhibition of cyclooxygenase-2 induced cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin-dependent kinase inhibitor p21. Br J Cancer, 86:1150-1156, 2002
Masuno H, Yamada K, Wang X, Choi M, Ooizumi H, Shinki T, Yamada S
Rational design, synthesis, and biological activity of novel conformationally restricted vitamin D analogues, (22R) and (22S)-22-ethyl-1,25-dihydroxy-23,24-didehydro-24a,24b-dihomo-20-epivitamin D (3). J Med Chem, 45:1825-1834, 2002
Kasuga H, Hosogane N, Matsuoka K, Mori I, Sakura Y, Shimakawa K, Shinki T, Suda T, Taketomi S
Characterization of transgenic rats constitutively expressing vitamin D-24-hydroxylase gene. Biochem Biophys Res Commun, 297:1332-1338, 2002
Katagiri T, Takahashi N
Regulatory mechanisms of osteoblast and osteoclast differentiation. Oral Diseases, 8:147-159, 2002
Kobayashi T, Chung U, Schipani E, Starbuck M, Karsenty G, Katagiri T, Goad DL, Lanske B, Kronenberg HM
PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development, 129: 2977-2986, 2002
Katagiri T, Imada M, Yanai T, Takahashi N, Kamijo R
Identification of a BMP-responsive element in Id1, the gene for inhibitor of myogenesis. Genes Cells, 7: 949-960, 2002
Johnsen SA, Subramaniam M, Katagiri T, Janknecht R, Spelsberg TC
Transcriptional regulation of Smad2 is required for enhancement of TGFβ inducible early gene. J Cell Biochem, 87:233-241, 2002
Shiotani A, Takami M, Itoh K, Shibasaki Y, Sasaki T
Regulation of osteoclast differentiation and function by receptor activator of NF-κB ligand and osteoprotegerin. Anat Rec, 268: 137-146, 2002
Rho J, Altman CR, Socci N, Merkov L, Kim N, So H, Lee O, Takami M, Brivanlou AH, Choi Y
Gene expression profiling of osteoclast differentiation by combined suppression subtractive hybridization (SSH) and cDNA microarray analysis. DNA Cell Biol, 21:541-549, 2002
Takami M, Kim N, Rho J, Choi Y
Stimulation by toll-like receptors inhibits osteoclast differentiation. J Immunol, 169:1516-1523, 2002
Li X, Udagawa N, Itoh K, Suda K, Murase Y, Nishihara T, Suda T, Takahashi N
p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function. Endocrinology, 143:3105-3113, 2002
Alam MS, Akaike T, Okamoto S, Kubota T, Yoshitake J, Sawa T, Miyamoto Y, Tamura F, Maeda H
Role of nitric oxide in host defense in murine salmonellosis as a function of its antibacterial and antiapoptotic activities. Infect Immun, 70: 3130-3142, 2002
Sahoo SK, Sawa T, Fang J, Tanaka S, Miyamoto Y, Akaike T, Maeda H
Pegylated zinc protoporphyrin: a water-soluble heme oxygenase inhibitor with tumor-targeting capacity. Bioconjug Chem, 13:1031-1038, 2002
Suda K, Woo JT, Takami M, Sexton PM, Nagai K
Lipopolysaccharide supports survival and fusion of preosteoclasts indipendent of TNF-α, IL-1, and RANKL. J Cell Physiol, 190: 101-108, 2002
Kim N, Takami M, Rho J, Josien R, Choi Y
A novel member of the leukocyte receptor complex regulates osteoclast differentiation. J Exp Med, 195: 201-209, 2002
Wang X, Wu J, Shidoji Y, Muto Y. Ohishi N, Yagi K, Ikegami S, Shinki T, Udagawa N, Suda T, Ishimi Y
Effects of geranylgeranoic acid in bone: induction of osteoblast differentiation and inhibition of osteoclast formation. J Bone Miner Res, 17: 91-100, 2002
Wu J, Akaike T, Hayashida K, Miyamoto Y, Nakagawa T, Miyakawa K, Muller-Esterl W, Maeda H
Identification of bradykinin receptors in clinical cancer specimens and murine tumor tissues. Intl J Cancer, 98: 29-35, 2002
Takahashi N, Udagawa N, Takami M, Suda T
Osteoclast generation. In Bilezikian JP, Raisz LG, Rodan GA (eds) Principles of Bone Biology, Second Edition, vol. 1, New York, USA, 2002, Academic Press, pp 109-126
Nakanishi Y, Kamijo R, Takizawa K, Toyoshima T, Nagumo M
Inhibitors of cyclooxygenase-2 suppressed the proliferation and differentiation of human leukemia cell lines. Eur J Cancer, 37: 1570-1578, 2001
Yanai T, Katagiri T, Akiyama S, Imada M, Yamashita T, Chiba H, Takahashi N, Suda T
Expression of mouse osteocalcin transcripts, OG1 and OG2, is differently regulated in bone tissues and osteoblast cultures. J Bone Miner Metab, 19: 345-351, 2001
Itoh K, Udagawa N, Katagiri T, Iemura S, Ueno N, Yasuda H, Higashio K, Quinn JM, Gillespie MT, Martin TJ, Suda T, Takahashi N
Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand. Endocrinology, 142: 3656-3662, 2001
Murase Y, Okahashi N, Koseki T, Itoh K, Udagawa N, Hashimoto O, Sugino H, Noguchi T, Nishihara T
Possible involvement of protein kinases and Smad2 signaling pathways on osteoclast differentiation enhanced by activin A. J Cell Physiol, 188: 236-242, 2001
Quinn JM, Itoh K, Udagawa N, Hausler K, Yasuda H, Shima N, Mizuno A, Higashio K, Takahashi N, Suda T, Martin TJ, Gillespie MT
Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions. J Bone Miner Res, 16: 1787-1794, 2001
Suda T, Kobayashi K, Jimi E, Udagawa N, Takahashi N
The molecular basis of osteoclast differentiation and activation. Novartis Found Symp, 232 : 235-247, 2001
Kotake S, Udagawa N, Hakoda M, Mogi M, Yano K, Tsuda E, Takahashi K, Furuya T, Ishiyama S, Kim KJ, Saito S, Nishikawa T, Takahashi N, Togari A, Tomatsu T, Suda T, Kamatani N
Activated human T cells directly induce osteoclastogenesis from human monocytes : possible role of T cells in bone destruction in rheumatoid arthritis patients. Arthritis Rheum, 44 : 1003-1012, 2001
Okamoto T, Akaike T, Sawa T, Miyamoto Y, van der Vliet A, Maeda H
Activation of matrix metalloproteinases by peroxynitrite-induced protein S-glutathiolation via disulfide S-oxide formation. J Biol Chem, 276: 29596-29602, 2001
